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mavorixafor will improve the amount or effect of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a strong CYP2D6 inhibitor) is contraindicated with drugs which have been hugely dependent on CYP2D6 for clearance.Extreme Allergic Reactions. Dextromethorphan may well bring about allergic reactions, which may be